Reports and Posters
In Vitro Dermal Absorption of Carfentanil
This study was presented in an e-poster at the 2020 Society of Toxicology Virtual Meeting.
Permeation of carfentanil formulated in three vehicles, water, ethanol, and hand sanitizer, was measured under infinite-dose conditions in an in vitro static diffusion cell system using the EpiDerm™ (EPI-606-X) RHE model. The permeation rate was fastest for carfentanil in water, followed by hand sanitizer, and slowest for carfentanil in ethanol. In ethanol and hand sanitizer, a lag-time between exposure and permeation of approximately 1 hour was observed, while the lag-time in water was 30 minutes. These data indicate that small skin exposures may not result in rapid significant toxicity as previously reported.
Methods for range finding experiments and reproductive and developmental toxicity tests with Peromyscus exposed to per- and polyfluoroalkyl substances (PFAS)
This study was presented in a poster at the SETAC North America Focused Topic Meeting Environmental Risk Assessment of Per- and Polyfluoroalkyl Substances.